The effects of endocrine treatment assisted elective surgery on the survival and life quality in patients with stage 2 endometrial carcinoma

Objective: We investigated the data of the survival and life quality in patients with stage 2 endometrial carcinoma who underwent endocrine treatment assisted elective surgery in order to confirm the clinical value and provide data support for its promotion. Methods: 183 selected endometrial cancer patients of stage 2 who were treated with surgery in our hospital from March 2009 to March 2010 were enrolled. They were divided into two groups by random number table method, and scheduled for elective surgery and endocrine treatment assisted elective surgery therapy, respectively. The clinical efficacy, complications, survival and life quality of the patients during follow-up were compared and analyzed. Result: Effective rate of the observation group and the control group was 94.6% and 86.8%, respectively, and the observation group was significantly superior to the latter (P < 0.05). The incidence of complications was separately 10.9% and 17.6%, and the observation group had a significant advantage as well (P < 0.05). 2 years, 3 years, 4 years as well as 5 years after operation, the number of survival cases in the observation group was remarkably higher than that in the control group (P < 0.05). The average scores of life quality after treatments were (3.5+70.6) and (63.4+4.1) respectively, and the observation group was also superior to the control group (P < 0.05). Conclusion: Endocrine treatment assisted elective surgery for endometrial carcinoma of stage 2 can improve the curative effect, reduce complications, prolong survival, and improve the recurrence rate and life quality. As a result, it is valuable for popularization.